RAG2 and infection: Additionally, all infection positive BALB/c RAG2−/−γc−/− mice (8/8 mice) but not infection negative RAG2−/− mice (0/9 mice) were seropositive for the distinct filarial adult antigen, Og4C3, 5 months after experimental infection (p < 0.0001, Mann–Whitney test, Fig. 1h).