Using IntOGen39, we identified 18 genes as putative driver genes in BL (ID3, TP53, CCND3, SMARCA4, FBXO11, ARID1A, DDX3X, GNA13, FOXO1, RHOA, TCF3, PCBP1, RFX7, E2F2, GNAI2, TFAP4, ADNP, and HNRNDP). The gene discussed is E2F2; the disease is Burkitt lymphoma.