This CpG site is located in a genomic region known as “Transcription start sites” (TSS200) that belong to the promoter region [38], and could be associated with an upregulation of MTOR, but this need to be demonstrated since there is evidence for cases where hypomethylation is associated with gene upregulation in autoimmune diseases [39,40] and early stages of tumorigenesis. The gene discussed is MTOR; the disease is autoimmune disease.