Examination of sera from ARDS and age-matched control individuals (Table S2) revealed no p18 in control individuals, but p18 generation in sepsis-associated ARDS (Figure 4N), with all patient sera that contained p18 IL-1α also positive for microbiology in bronchoalveolar lavage fluid (Figure 4N and Table S3). The gene discussed is IL1A; the disease is Sepsis.