We found that the proportion of CTLs in dLNs from the si-Pvt1 group was much higher than that in dLNs from the si-NC group, and the proportions of CTLs and Th1 cells in tumor tissues exhibited a moderate increase in the si-Pvt1 group compared with the si-NC group (Fig. 4b and c). The gene discussed is PVT1; the disease is neoplasm.