Functional classification of these genes showed enrichment for genes belonging to various cancer-related pathways; many of them are in agreement with the miR-96-5p biological role related to the cell migration and resistance to adjuvant therapy demonstrated in HNSCC cells, as the focal Adhesion, extracellular matrix organization and PI3K-Akt-mTOR-signaling pathway (Table 1). Here, AKT1 is linked to head and neck squamous cell carcinoma.