RRM1 and non-small cell lung carcinoma: Some molecular predictive markers have been applied for NSCLC patients with platinum-based chemotherapy, such as excision repair cross-complementing 1 (ERCC1) [34], ribonucleotide reductase subunit M1 (RRM1) [35], class III β-tubulin (TUBB3) [36] and breast cancer 1 (BRCA1) expression [37].