Our results showed that compared with CAD patients, the phosphorylation levels of AKTSer473, AMPKαThr172, and β-cateninser675 were sharply decreased in the aorta of TAAD patients, while p-mTOR, and non-p-β-catenin maintained similar levels between the two groups (Fig. 5a and b). The gene discussed is MTOR; the disease is coronary artery disorder.