CTSB and obesity due to melanocortin 4 receptor deficiency: As we found that obesity did not influence renal mass parameters and N-acetyl-β-d-glucosaminadase and Cathepsin B activity in the classes of Compliant GDM mother neonates, and, mostly, in Class 2 compared to Classes 1 and 3 of the Noncompliant GDM mother neonate subgroup, we then investigated if these trends were related to maternal weight gain, as this parameter influences fetal health [44,45,46,47].