IL18 and renal cell carcinoma: Although the sample size of the current study was similar to theirs (case:control = 92:580 vs. 158:506), we brought forward two novel findings: IL-18 -607 was a determinant of RCC susceptibility (Table 2 and Table 3), and there were positive interactions of this polymorphic site with personal behavioral and clinical factors (Figure 1, Figure 2, Figure 3 and Figure 4).