To explain in detail, the IL-18 -607 heterozygous AC and homozygous CC genotypes were associated with decreased risks for RCC (OR = 0.44 and 0.35, 95% CI = 0.27–0.72 and 0.18–0.66, p = 0.0008 and 0.0010, respectively) (Table 2, middle panel). The gene discussed is IL18; the disease is renal cell carcinoma.