The adjusted ORs for carriers with genotypes AC and CC at IL-18 -607 were 0.44 and 0.35 among subjects without diabetes (95% CI = 0.28–0.81 and 0.21–0.68, respectively) and 0.38 and 0.36 among those with diabetes (95% CI = 0.18–1.02 and 0.13–1.58, respectively), respectively (Figure 4). This evidence concerns the gene IL18 and diabetes mellitus.