B3GAT1 and hematologic disorder: In the same way, other studies have described an association between the higher cytotoxicity of HNK1 haplotype (equivalent to NK-2 Hb-1 haplotype in this study) and a better clinical outcome in standard risk hematologic malignancies after bone marrow transplant of unrelated HLA compatible donors [38], as well as a reduced risk of developing colorectal cancer [39,40].