EGFR and non-small cell lung carcinoma: Following 24 h of treatment, MG3 at 16 μM significantly induced apoptotic cell death in A549 cells, whereas MG3 at 2 μM induced significant apoptosis in H1975 cells (Figure 3A,B), indicating that apoptosis-inducing effect of MG3 was more pronounced in NSCLC cells carrying mutant EGFR than in NSCLC cells carrying wild-type EGFR.