Hypoglycaemia remains a common side‐effect of diabetes treatment with insulin and is associated with a range of morbidities, including falls and accidents, and adverse cardiovascular events.1 Severe hypoglycaemia, for which the individual requires external assistance (aid from another person to actively administer carbohydrate or parenteral therapy), is also associated with seizures, coma and increased risk of mortality.1 This evidence concerns the gene INS and type 2 diabetes mellitus.