MiR‐593 has been reported to be related to cisplatin sensitivity in tongue squamous cell carcinoma and radiosensitization in nasopharyngeal carcinoma cells.41, 42 The miR‐593 and PLK1 interaction were investigated in esophageal carcinoma,43 the tumor‐promoted effect was similar to that seen in our study on glioma cells. This evidence concerns the gene PLK1 and central nervous system cancer.