CEP290 which interacts with TALPID3 is also associated with a variety of ciliopathies with overlapping clinical features including Joubert syndrome, Joubert syndrome‐related disorders (JSRDs) 21, Meckel–Gruber syndrome (MKS) 22, and Bardet–Biedl syndrome (BBS) 23. This evidence concerns the gene KIAA0586 and Bardet-Biedl syndrome.