The “abscopal effect”, a phenomenon by which metastatic lesions outside the irradiation field show reductions in size, suggests some form of underlying immunological response.49 Homma et al50 reported that neoadjuvant chemoradiotherapy (NACRT) consisting of gemcitabine plus S‐1 followed by 30 Gy radiation for pancreatic cancer enhances both CD4+ and CD8+ TILs. Here, CD4 is linked to pancreatic neoplasm.