FOS and hypertensive disorder: Fos staining in the MnPO of the Gi DREADD + CNO + HTN group (n = 6 rats, two to four MnPO sections per rat) was significantly increased as compared to either of the CTRL groups injected with 0.9% SAL (CTRL + CNO + 0.9% SAL, n = 6 rats, two to four MnPO sections per rat; CTRL + VEH + 0.9% SAL, n = 6 rats, two to four MnPO sections per rat; p = 0.019 and p = 0.006, respectively).