For instance, Favaro et al. demonstrated that BM-MSC-EVs can skew monocyte-derived DCs toward an immature, IL-10-producing regulatory phenotype that associates with decreased levels of co-stimulatory molecules and increased IL-6, TGF-β, and PGE2 production in patients with type 1 diabetes [50]. Here, IL10 is linked to type 1 diabetes mellitus.