RPS6KB1 and diabetic cardiomyopathy: In ischemca/reperfusion injury and diabetic cardiomyopathy, AMPK-mTOR-p70S6K signaling was detected to induce the protective autophagy by ischemic postconditioning, indicating the involvement of AMPK-mTOR-p70S6K signaling-mediated autophagy [42,43].