In 1999, since Hubacek et al. [15] first reported that CD14 gene single nucleotide polymorphism (SNP) rs2569190, related to the translation start site at upstream of promoter region, was apparently relevant to atherosclerosis in the Czech population, the allele T of rs2569190 was also reported being a risk factoring for MI in European population. Here, CD14 is linked to atherosclerosis.