SOX11 and head and neck squamous cell carcinoma: As presented in Fig. 5C, overexpression of wild-type SOX11 induced the expression of SDCCAG8 in low invasive HNSCC cells (UM2 and UMSCC6) whereas over-expression of mutant SOX11 (Sox11FΔTAD) abolished the expression of SDCCAG8 in highly invasive HNSCC cells (UM1 and UMSCC5).