PCDH17 and acute myeloid leukemia: Further comparing PCDH17 expression between CD34+ AML and CD34+ normal samples in two independent datasets (GSE24006 and GSE30029), we also detected a significant reduction of PCDH17 expression in CD34+ AML cells (GSE24006, n = 16; GSE30029, n = 46), as compared with CD34+ normal cells (n = 31 for both datasets) (Fig. 2a).