In CN-AML patients, PCDH17 down-regulation was still an independent poor prognostic factor for OS (HR = 2.02; 95% CI 1.13–3.62; P = 0.02) and a borderline poor prognostic factor for DFS (HR = 1.79; 95% CI 0.93–3.44; P = 0.08). This evidence concerns the gene PCDH17 and acute myeloid leukemia.