ACTA1 and neoplasm: On average, αSMA, PDGFRβ and CD31 were not differently expressed between the tumor center (αSMA M = 0.122, SE = 0.019; PDGFRβ M = 0.152, SE = 0.034; CD31 M = 0.014, SE = 0.005) and the invasive part (αSMA M = 0.092, SE = 0.014; PDGFRβ M = 0.134, SE = 0.026; CD31 M = 0.010, SE = 0.002; P > 0.05) (Fig. 3c).