While IL-8, a chemokine secreted by many cell types, including monocytes, neutrophils, epithelial cells, fibroblasts, endothelial cells, mesothelial cells and tumour cells in response to inflammation (Matsushima and Oppenheim 1989), acts as a chemotaxis agent in mobilizing T cells as well as other non-specific inflammatory cells to inflammation site (Schröeder 1992). This evidence concerns the gene CXCL8 and neoplasm.