NFE2L2 and metabolic dysfunction-associated steatotic liver disease: Given the central role of oxidative stress in the development of NAFLD, we analyzed the expressions of Nrf2 (a crucial transcription factor that induces the expression of antioxidant enzymes and phase II detoxifying enzymes), Nrf2-regulated antioxidant gene (HO-1) and antioxidant enzymes (such as CAT activity, reduced-GSH level), as well as the GSSG/GSH ratio and MDA in the liver.