Inflammation [4,5], renal and cardiovascular disease [6–8] are major triggers of the production of fibroblast growth factor 23 (FGF23), a proteohormone mainly produced in the bone [9] and implicated in the regulation of phosphate reabsorption and 1,25(OH)2D3 (active vitamin D [10]) formation in the kidney [11]. Here, FGF23 is linked to cardiovascular disorder.