Higher expression of lncRNA H19 was observed in colon cancer and significantly correlated with tumour differentiation and poor overall survival and poor disease‐free survival of CRC patients.35 A recent study by Geng et al also demonstrated increased H19 in inflamed intestinal tissues from mice and patients.19 Our results indicated that H19 was up‐regulated in inflamed colon tissues and CRC tissues. The gene discussed is H19; the disease is malignant colon neoplasm.