Crybb2 is also expressed in the brain (Magabo et al. 2000; Ganguly et al. 2008), and in homozygous Crybb2 mutants, parvalbumin-positive interneurons as well as dendrites and dendritic branches in the hippocampus are decreased (Sun et al. 2013, 2018), and eventually changes in schizophrenia-related endophenotypes have been observed (Heermann et al. 2018). The gene discussed is CRYBB2; the disease is schizophrenia.