GFI1 and plasma cell myeloma: Gfi1 is a SNAG (Snail/Gfi1) domain‐containing C2H2 zinc‐finger involved in differentiation of lymphoid and myeloid cells39 and new research suggests its deregulation in various hematologic malignancies including myeloma.40, 41, 42, 43 BMSCs exposed to MM cocultures or harvested from either a murine MM model or MM patients have increased Gfi1 expression.