GDF10 and posterior cortical atrophy: This was reported to be through the osteoblast‐secreted factors growth differentiation factor 10 (GDF10) and transforming growth factor‐beta 2 (TGFβ2), which induced PCa tumor cell dormancy in bone through activation of the signaling pathway TGFβRIII–p38MAPK–pS249/pT252–RB.47, 50 Furthermore, lower levels of TGFβRIII were found to correlate with metastatic progression and a worse clinical outcome in PCa patients.50