Bioinformatic analysis (cBioPortal/TCGA datasets) of CLIC1 mRNA levels in several human aggressive carcinomas (breast, colorectal, esophagus, liver, ovarian, stomach, prostate, thyroid, uterine, head & neck, and pancreas) shows that this channel is expressed at similar levels in all the different types of neoplasia, with a small increment only in colorectal, head & neck and pancreatic cancers (Figure 1). The gene discussed is CLIC1; the disease is neoplasm.