PRL and Familial prostate cancer: As can be seen in Table 3, the top 15 KEGG pathways linked to naringenin-mediated proteins were identified and included steroid hormone biosynthesis, metabolism of xenobiotics by cytochrome P450, chemical carcinogenesis, drug metabolism-cytochrome P450, retinol metabolism, pentose and glucuronate interconversions, ascorbate and aldarate metabolism, ovarian steroidogenesis, drug metabolism-other enzymes, porphyrin and chlorophyl metabolism, prolactin signaling pathway, thyroid hormone signaling pathway, estrogen signaling pathway, metabolic pathways, and prostate cancer.