In bladder cancer, Xue et al. demonstrated that UCA1 induced epithelial–mesenchymal transition (EMT) of bladder cancer cells through up-regulating the expression of zinc finger E-box binding homeobox 1 and 2 (ZEB1 and ZEB2), and also regulated cell migration and invasion of bladder cancer by suppressing miR-145 and its target gene the actin-binding protein fascin homologue 1 (FSCN1) [48]. This evidence concerns the gene ZEB1 and urinary bladder cancer.