Knockdown of Rab35 under double RNAi conditions did not significantly lower levels of Puc-LacZ expression relative to double knockdown controls in either early or late SC CCs, suggesting that Rab35 may act downstream rather than upstream of activated JNK to enable cyst cells to kill neighboring spermatocytes (Fig. 7E-G). The gene discussed is RAB35; the disease is cyst.