Because knockdown of Rab35 in cyst cells did not reduce activation of the JNK pathway in cyst cells but still partially prevented germ cell death when somatic cyst cells lose Par complex function, one possibility is that Rab35 function may be required to carry a product downstream of JNK pathway activation to the plasma membrane that faces the germ line, e.g. a pro-mitotic signal, as proposed above (Fig. 7I). Here, MAPK8 is linked to cyst.