These findings were reflected in univariate logistic regression analyses of logistic-transformed methylation β-values (M-values; Table 6) in the entire TCGA dataset (n = 478), where ASB2 methylation probes were unique in exhibiting significant association with tumor status based on decreased, rather than increased, methylation values (ORs ranging from 0.09 to 0.30). Here, ASB2 is linked to neoplasm.