CSF3 and bacterial infectious disease: The key role of G-CSF in the resolution of bacterial infections has been shown in various mouse models of bacterial infections [82] including L. monocytogenes and Pseudomonas aeruginosa. Thus, granulopoïesis increases at the expense of lymphoid progenitor cells [83] through the induction of HSPC (hematopoietic stem and progenitor cell) compartment reactivation [84].