TNF and colorectal carcinoma: Western blotting analysis showed that in CRC cells, TNF-β, similar to TNF-α, reduced the epithelial marker (E-cadherin) and elevated the mesenchymal markers (vimentin) and EMT-related transcription factor (slug) on the protein level, and resveratrol alone or in co-treatment with TNFs significantly decreased vimentin and slug levels and increased E-cadherin expression (Figure 1B).