Enrichment Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis revealed DEGs engaged into three metabolic pathways: NF-kappa B signaling pathway (ZAP70, LCK, LTB), T cell receptor signaling pathway (ITK, ZAP70, LCK), and primary immunodeficiency (ZAP70, IL7R, LCK). The gene discussed is LCK; the disease is inborn error of immunity.