PRKCD and Sepsis: Our recent studies demonstrate that PKCδ Tyr-155 and PKCδ Tyr-311 are phosphorylated during sepsis and play key roles in sepsis-induced lung injury, the regulation of microvascular endothelium barrier function, and neutrophil-endothelial cell interactions (See Section 2.2.3 and Section 2.2.4) [21,24].