Thus, the proteasome system seems to play an important role in the regulation of AR activity and can be proposed as a unique target for the development of therapeutic drugs blocking androgen/AR‐mediated prostate tumour growth.34 Because translation is the final step in the production of a functional protein, alterations in translational control may represent an ‘oncogenic' node which may serve as a potential target for tumour suppression. The gene discussed is AR; the disease is neoplasm.