In our study, we also found that patients with anti-Jo-1, anti-PL-7, anti-EJ, and anti-MDA5 antibodies are more likely to have interstitial lung disease, while the DM patients with an anti-TIF1-γ antibody mainly were without ILD (Table 1), which is consistent with previous studies [12, 38]. The gene discussed is IFIH1; the disease is dermatomyositis.