In a previous study by our group, we have reported increased co-expression of epithelial cytokeratin 8 (CK8) and mesenchymal vimentin (Vim) markers in androgen-independent PLum-AI murine PCa cell lines, which represent advanced stages of PCa, referring to a positive EMT status in those cells, when compared to androgen-dependent PLum-AD cells which represent primary PCa (27). The gene discussed is VIM; the disease is posterior cortical atrophy.