In surgery for hepatocellular carcinoma, Sun et al. [38] found that compared with intravenous inhalation-combined anesthesia, after the surgery for hepatocellular carcinoma, there is a significant increase in the amount of CD4+/CD8+ T cells when patients use general anesthesia combined with epidural anesthesia. The gene discussed is CD8A; the disease is hepatocellular carcinoma.