SYPL1 and Canavan disease: Among other genes of interest appearing in the set of 30 are aspartoacylase (ASPA) which maintains white matter and dysfunction of which is a cause of Canavan disease (Bitto et al., 2007); doublecortin like kinase 1 (DCLK1), which is involved in neuron migration and neurogenesis (Deuel et al., 2006); potassium calcium-activated channel subfamily M alpha 1 (KCNMA1) which has been associated with LOAD (Grupe et al., 2006) and schizophrenia (Zhang et al., 2006); and synaptophysin like 1 (SYPL1) which is involved in neuronal differentiation (Leube, 1994).