TRIM21 and Sjogren syndrome: Clinically, it has been suggested that different associations of anti-Ro60 (Ro60 Ab) or anti-Ro52 antibodies (Ro52 Ab) in patients may associate with different phenotypes such as systemic lupus, neonatal lupus, and fetal atrioventricular blockade, primary Sjögren's syndrome, or inflammatory myositis (9–24).