In contrast, when we compared NETs from RA and SLE neutrophils stimulated with A23187, six NET proteins were higher in RA NETs, including CAMP, CRISP3, CXCL8, and MMP8, and 13 NET proteins were higher in SLE NETs, including histones H1.0, H2B (type 1-J), H2B (type 2-F), and H4 (Supplementary Table 5). The gene discussed is MMP8; the disease is systemic lupus erythematosus.