The interaction between thyroid hormone and integrin αvβ3 (11) has been demonstrated to promote cancer cell proliferation in various types of cancer cells, including breast cancer (12, 13), lung cancer (10, 14), glioma cells (15, 16), myeloma cells (17), pancreatic cancer (18), and colorectal cancer cells (6, 7, 13, 19). The gene discussed is TG; the disease is colorectal cancer.