ABCB1 and renal carcinoma: P-glycoprotein 1 (P-gp1), also known as multidrug resistance protein 1 (MDR1) or ATP- binding cassette sub-family B member 1, is highly polymorphic and several studies have reported that carriers of the T-allele for the genetic variation C3435T (rs1045642) have an increased risk of colon, breast, and renal cancer (Phuthong et al., 2017).