Variable rates of psychiatric illnesses, generally less common than in c9orf72 repeat carriers, were also observed in non-c9orf72 ALS-FTD cases, carrying PRGN (Hall and Finger, 2015), TBK1 (Van Mossevelde et al., 2016), and VCP (Weihl, 2011) mutation. This evidence concerns the gene TBK1 and frontotemporal dementia.