In the remaining fusion transcripts other fusions could explain the overexpression of driver genes such as COMMD3-BMI1, LMO1 or JAK3. Four fusions found exclusively in tumour samples could be considered pathogenic (RIC3-TCRBC2, SLC35A3-HIAT1, PICALM MLLT10 and MLLT10-PICALM). The gene discussed is TRBC2; the disease is neoplasm.